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  • Patent ductus arteriosus (PDA) is a heart defect that occurs when the ductus arteriosus (an opening between the aorta and the pulmonary artery) fails to close at birth. A PDA is usually diagnosed when your veterinarian hears a continuous heart murmur during a routine physical examination of your puppy. This article explains PDA and discusses signs, treatment, and prognosis for this condition.

  • Pemphigus is an autoimmune skin disease in which the body's immune system attacks the connections between its own skin cells. The three most common types of pemphigus are pemphigus foliaceus, pemphigus vulgaris, and pemphigus erythematosus. Treatment requires suppression of the immune system and prognosis varies depending on the type.

  • Perianal fistula, also known as anal furunculosis is a serious medical condition that most commonly affects German Shepherd dogs. Perianal fistulas are characterized by chronic, purulent, smelly, ulcerating, sinus tracts in the anal region and surrounding skin. More recent studies indicate that the condition is more likely caused by an autoimmune disease. Medical management with immune-modulating drugs is now the preferred therapy. In severe cases, surgery is required to debride or remove as much infected tissue as possible.

  • Pericardial effusion refers to the abnormal accumulation of fluid in the sac surrounding the heart. Pericardial effusion can have a number of underlying causes, including inflammation, infection, cancer, and hereditary defects. Mild cases of pericardial effusion may be asymptomatic, but more significant fluid accumulations can interfere with the heart’s function and lead to severe effects such as sudden death. Treatment and prognosis is dependent upon the underlying cause of the condition.

  • Pets may have visible or hidden disabilities that require some adjustments to their care or lifestyle to maximize their quality of life. With some support, these pets can have a fairly normal life and be just as loving as any other pet.

  • Pigmentary keratitis is a discoloration of the cornea due to chronic inflammation and is most common in brachycephalic breeds. In many cases, complete resolution cannot be achieved, but the condition can be stopped or slowed down if the underlying cause can be identified and treated. Surgery and medications may be used to help address the problem.

  • Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The clinical signs depend on the type of macroadenoma, though become severe over time in either case. Diagnosis requires specialized CT or MRI imaging. This handout explains the effects of macroadenomas in cats and the treatment options available.

  • Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The most common functional pituitary macroadenoma in the dog secretes the hormone ACTH, causing increased cortisol levels and Cushing’s disease. Non-functional macroadenomas cause clinical signs through compression of nearby structures resulting in vision changes, diabetes insipidus, and neurologic disorders. This handout explains the effects of these tumors on dogs, how they are diagnosed, and the treatment options available.

  • Pleural effusion refers to the abnormal accumulation of fluid within the chest cavity. The fluid is not found within the lungs, but instead within the pleural sac, essentially meaning the lungs are floating in a chest that is full of fluid. Several conditions can cause pleural effusion, including chylothorax, heart failure, and tumors in the lungs or chest wall. Immediate treatment often requires oxygen support and the removal of the excess fluid by thoracocentesis, which can also then be tested to diagnose the cause of the pleural effusion. Treatment and prognosis vary depending on the underlying cause of the pleural effusion.

  • Pleural effusion refers to the abnormal accumulation of fluid within the chest cavity. The fluid is not found within the lungs, but instead within the pleural sac, essentially meaning the lungs are floating in a chest that is full of fluid. There are several causes, including chylothorax, heart failure, and lung or chest tumors. Dogs presenting for pleural effusion are often experiencing shortness of breath and decreased oxygen intake; placing them into an oxygen cage provides some degree of immediate relief. Removing the fluid that surrounds the lungs will allow the dog to breathe more readily and this fluid can then be tested to identify the cause of the pleural effusion. The treatment and prognosis vary depending on the underlying cause.